We are happy to announce that Dr. Izabela Zaborniak, a member of the Chmielarz Research Group and deputy supervisor of KN IPSUM, has been recognized as one of the leaders of winning projects in the XIV competition of the LIDER Program, funded by the National Centre for Research and Development! The project budget is PLN 1 700 635.00 PLN.
Dr. Zaborniak, in the course of project implementation, will obtain precisely defined branched polymers consisting of a sucrose core and eight polymeric side arms constructed from copolymers belonging to the acrylate group. These copolymers include both ionic monomers containing cationic and anionic side chains, as well as non-ionic ones. For this purpose, she will apply atom transfer radical polymerization (ATRP) method because this group of techniques allows for designing polymers with a well-defined structure, providing the possibility of precisely modulating the release of active substances depending on the composition and length of the polymer arms.
The synthesized polymers will be examined for their applications as auxiliary substances for modified drug release, in collaboration with a pharmaceutical company, where developmental studies will be conducted as a stage in preparing the products obtained within the project for market implementation. The presence of ionic monomers in the side chains of the polymers determines the mechanism of active substance release in specific segments of the digestive system. On the other hand, the use of non-ionic polymers affects the physicochemical properties of the final form of the polymer material, increases the bio-compatibility of the polymer, and modulates its solubility.
The mentioned project is a response to the pharmaceutical market's demand for auxiliary chemical substances that enhance therapeutic effects. Currently, this goal is achieved through changes in the method of administering medicinal substances, so the drug form technology serves as an excellent tool for optimizing pharmacotherapy based on already-existing active substances in the market.
Congratulations, and we wish you further success! ❗️
For more information about the Program visit:
https://www.gov.pl/web/ncbr/lider-xiv---wyniki-oceny-merytorycznej-wnioskow-zlozonych-w-konkursie
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